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PURPLE

A purity, ploidy and copy number estimator for whole genome tumor data

https://github.com/hartwigmedical/hmftools/

PURPLE combines B-allele frequency (BAF), read depth ratios, somatic variants and structural variant breakpoints to estimate the purity and copy number profile of a tumor sample, and also predicts gender, the MSI status, tumor mutational load and burden, clonality and the whole genome duplication status.

File search patterns​

purple/purity:
  fn: "*.purple.purity.tsv"
purple/qc:
  fn: "*.purple.qc"